

https://www.tandfonline.com/doi/pdf/10.2147/AHMT.S135432
Evidence from the 10 available
prospective follow-up studies from childhood to adolescence
(reviewed in the study by Ristori and Steensma28) indicates
that for ~80% of children who meet the criteria for GDC,
the GD recedes with puberty
Puberty blockers are a strong change in your life and a severe intrusion into the natural development of a body. Instead of going through puberty like most other kids, the child will be behind in their physical development by years. That can lead to social and psychological problems of course.
There’s generally not much quality research into the long term effects, as you can read repeatedly in [the Wikipedia article](https://en.wikipedia.org/wiki/Puberty_blocker#Research).
As for transitioning not resolving the psychological issues, those choosing to detransition are the best proof. https://segm.org/first_large_study_of_detransitioners
The participants’ decision to detransition was most often tied to the realization that their gender dysphoria was related to other issues (70%), health concerns (62%), and the fact that transition did not alleviate their dysphoria (50%). Interestingly, over 4 in 10 (43%) participants endorsed a change in political views as a reason for detransition.
Most participants reported significant difficulties finding the help that they needed during their detransition process from medical, mental health, or LGBT communities. Only 13% of the respondents received help from LGBT organizations when detransitioning, compared to 51% when transitioning. A number of participants reported negative reactions from LGBT and medical communities, and 51% of the sample expressed that they did not feel supported during their detransition.
Most detransitioners reported ongoing needs related to managing comorbid mental health conditions (65%), finding alternatives to medical transition (65%), and coping with regret (60%). Half of the sample reported the need for medical information on stopping or changing hormone regimens. A great majority of participants also expressed the need to hear about others’ detransition experiences (87%) and getting in contact with other detransitioners (76%). The study highlights the urgency of providing appropriate medical, psychological, legal, and social support to detransitioners.
I haven’t bothered to look for data concerning the long term mental health of those who transition. I only have lots of anecdotes from conversations with trans folk over the years. That’s of course not representative.
https://pubmed.ncbi.nlm.nih.gov/36151828/
Our findings coincide with existing research, which indicates TG individuals do experience a higher prevalence of mental health disorders than that of the general population or cisgender individuals


It’s not about invalidation. It’s about the case of lost and mentally unwell people finding out about transgender, then find a welcoming community, that accepts them. They get presented a simple explanation on why they don’t feel like themselves and a path through that. If other people (like the parents) shed doubt on this, they can be called transphobic and face social consequences. So if someone grabs onto this, they get treatment in the form of hormone pills pretty much immediately under informed consent.
Differential diagnosis for mental health issues is never easy. One mental health issue can easily cause others. The major difference is that gender and being trans can become a big part of one’s identity. You don’t get that to that extent with other disorders.
Especially the overlap with autism is interesting and not obviouS. https://www.cambridge.org/core/journals/european-psychiatry/article/crossing-boundaries-unraveling-the-link-between-gender-dysphoria-and-autism/DB33E9208EF32A46C4AE83D9B673F498
I invite you to seek out interviews with detransitioners and people who used to work in gender affirming care, if you want to learn about Trans issues from someone besides activists.
That said trans people are real and some benefit from transitioning. The very charged political climate around this health care issue, creates problems for trans and non trans folk alike.