So what? Most of us were never meant to be impactful, or even lack the ability to be impactful. I would posit that life in general was only ever meant for us to vibe with the universe for a brief time. In the span of epochs, and especially once humanity makes itself extinct, vanishingly little will have any material impact on even the planet, much less reality as a whole.

Unless you manage to trigger false vacuum decay. Then you have made the biggest possible impact by destroying the entire universe. Not sure this is an appropriate goal to reach for, but hey. You do you.